Case Studies

Case 1: Aphasia due to Cerebral Infarction

This 64-year-old woman had sustained a left hemispheric cerebral infarction eight years earlier. She was left with a residual fluent aphasia that interfered significantly with her ability to communicate.

Case 2: Visuo-Spatial Impairment and Psychosis due to Encephalitis

This 19-year-old man presented with an acute onset of delusions and hallucinations. Despite his psychotic symptoms, he was able to cooperate with testing. The Cognistat profile showed a marked constructional disability with additional problems in calculations and similarities. This testing pre

Case 3: Amnestic Syndrome due to Chronic Alcohol Abuse

A 52-year-old man with a long history of severe alcohol abuse had experienced several episodes of alcoholic hallucinosis. At the time of admission to the hospital he was thought to have a global dementia.

Case 4: Reversible Dementia due to Hepatic Encephalopathy

A 56-year-old man with a history of liver disease entered the hospital for surgery but his protein-restricted diet was inadvertently discontinued.

Case 5: Mild Cognitive Impairment (MCI Index = 2)

This older woman with mild memory impairment was diagnosed as having Mild Cognitive Impairment, based on a comprehensive neuropsychological battery and Cognistat. Her Cognistat MCI Index score of 2 falls in the mid range ("suggests MCI") for MCI and is based on her age of 75, an isolated impair

Case 6: Mild Cognitive Impairment (MCI Index = 3)

This 63-year-old woman was diagnosed as having Mild Cognitive Impairment based on testing with both Cognistat and a comprehensive neuropsychological battery.

Case 7: Dementia Syndrome (MCI Index = 4)

This mixed dementia syndrome case is from a 77-year-old retired computer systems analyst with a three-year history of visual "hallucinations" or misperceptions and memory problems. His wife expressed concern about his daily alcohol use.

Case 8: Dementia Syndrome (MCI Index = 5)

This mixed dementia syndrome case is a 76-year-old retired investment advisor with an MBA from Stanford, who had been diagnosed with a dementia two years earlier. His wife suggested that he had shown a very slow progression of cognitive symptoms during this time.

Case 9: Dementia Syndrome (MCI Index = 5)

This 82-year-old woman presented with a five-year history of gradually increasing problems with memory. Neurologic examination was unremarkable and a full battery of neurodiagnostic tests for treatable causes of dementia was negative. Cognistat revealed multiple areas of intellectual dysfunctio

Case 10: Dementia Syndrome (MCI Index = 6)

This mixed dementia syndrome case is a 78-year-old retired Master's level social worker with a recent history of problems with verbal fluency and memory. She had been on hormone replacement therapy since menopause.

Case 11: Amnestic Dementia Syndrome (MCI Index = 4)

This 41-year-old college-educated former professional football player retired before the age of 30 due to multiple knee injuries. His wife requested evaluation of her husband 15 years later because of her concerns that he might have chronic traumatic encephalopathy (CTE) related to innumerable c

Case 12: Amnestic Dementia Syndrome (MCI Index = 4)

Case 12 is a 56-year-old college-educated professional football player who played for more than 10 years and sustained 20-30 concussions; 3 with frank loss of consciousness. He suffered from chronic headaches, multifocal joint pain, an inability to follow conversations and was dependent on his w

Case 13: Impairments in Registration and Working Memory (MCI Index = 6)

Case 13 is an 88-year-old twice-widowed woman with 11 years of education. Her medical history is of note for atrial fibrillation, a myocardial infarct, type II diabetes, a bowel resection for cancer and a recent head injury from a fall.

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